[目的/意义]社交媒体上的高影响力用户可能会引导突发事件的舆论走向，对事件的后期演变及结果产生积极或消极作用，识别并刻画高影响力用户特征对于突发事件的网络舆情管理具有重要的理论价值与现实意义。[方法/过程]本文将社交媒体高影响力用户划分为“话题发起者”“意见领袖”“意见扭转者”三种角色，提出基于主题一致性与情感支持的社交媒体高影响力用户的画像方法，以“贺建奎基因编辑婴儿事件”为例，识别不同类型的高影响力用户，揭示各类用户的观点差异及动态变化，构建高影响力用户的完整画像。[结果/结论]研究发现有助于突发事件管理部门识别掌握社交媒体关键用户的关注点与态度，为舆情管理与应急决策提供方法与数据支持。

[Purpose/significance] The users of high influence on social media platforms may lead the public opinion about public emergencies, and have positive or negative effects on the later evolution of events and their results. Identifying high-influence users on social media platforms is of great theoretical and practical significance in managing the online public opinion about public emergencies. [Method/process]In this study, high-influence users are categorized into three types, i.e. the topic initiator, opinion leader, and opinion reverser. The method of profiling high-influence users has been proposed based on topic consistency and emotional support. The event of "Jiankui He Editing the Infant’s Gene" was investigated. The three types of high-influence users were identified and their opinion differences and dynamic evolution were revealed. The comprehensive profiles of high-influence users were constructed. [Result/conclusion]The findings of this study can help emergency management departments master the focus of attention and emotional attitudes to the public emergencies by the key users of social media and provide method and data support for opinion
management and decision-making of emergencies.