[Purpose/significance] This paper reviews the existing online health information behavior experimental research at home and abroad, and provides design ideas and application suggestions for future relevant experimental research, and promotes the scientificity of research methods and the richness of research content in the field of online health information behavior. [Method/process] According to the paradigm of experimental research in the field of social science, we code and analyze 63 literatures with NVivo qualitative analysis software. On this basis, a more standard and practical construct paradigm of experimental research on online health information behavior is summarized. Finally, this paper makes prospects aiming at the longitudinal application of construct paradigm and the horizontal expansion of research contents. [Result/conclusion] In the future, the experimental research on online health information behavior can focus on: pursuing the systematicness of individual study and the pertinence of group research; exploring the interaction of online behavior and the particularity of information behavior; avoiding the tropism of experimental subjects and the intention of experimenters; valuing the integration of research methods and the multi-dimension of research data.