[Purpose/significance] This paper aims to systematically review and analyze the outcomes of foreign researches on the dark side of information system use on users’well-being, which can lay a foundation for understanding the relationship between information system use and user health. [Method/process] This paper reviews the dark side of information systems on mental health from the perspective of impact types, including social fatigue, Internet addiction, other negative effects. Meanwhile, this paper reviews the dark side of information systems on physical health from the perspective of impact path, including the direct and indirect effects of information system use and the moderating effect of demographic indicators. [Result/conclusion] Our study find that the current research lacks the subdivision of information system functions, and the research results lack reasonable theoretical support. Most of the research objects involve young and healthy students, which makes other users of information system neglected. This paper lays a foundation for the follow-up research in China from the perspectives of focusing on socially disadvantaged groups, refining the functions of information systems, combining longitudinal user data, and attaching importance to theoretical research.