Abstract: [Purpose/significance] The online medical crowdfunding is a new form of charity in the network, which isof great significance for individual social assistance and the cultivation of charitable atmosphere. However, there is stilla lack of research on the motivation of avoidance behaviors on online medical crowdfunding information. [Method/process] Considering the health information attributes and social information attributes of online medical crowdfunding information, this study constructs its influential factors model based on the extended parallel process model and motivated information processing theory, and conducts empirical analysis by using questionnaire survey and structural equation model. [Result/conclusion] The results show that the information avoidance behavior of online medical crowdfunding is positively affected by perceived fear and negatively affected by prosocial motivation. Among them, trust in crowdfunding information positively affects prosocial motivation, while perceived fear comes from the assessment of information threat.