[Purpose/significance] Scientific data harmonization is an effective way to solve major economic and social problems across disciplinary boundaries. Its purpose is to realize the opening and sharing of data in the whole disci? pline, whole process and panorama of integrated scientific research. FAIR principle points out the specific implementa? tion norms for scientific dataharmonization. [Method/process] Using the method of literature investigation, the con? cept of scientific data harmonization is differentiated; scientific data harmonization path is analyzed based on the FAIR principle; on the basis of important progress in different branches of scientific data field at home and abroad，multi-per? spective of relational mapping model of scientific data harmonization practice synergy scheme, including technology and tools, policies and guidelines, patterns and actions?is constructed from macro, meso and micro three levels. [Re? sult/conclusion] This paper proposed that future research should consider the problems existing in the process of scien? tific data opening and sharing from the perspective of harmonization network, and explore the scientific data harmoniza? tion system, coordination mechanism, pattern strategy and implementation effect of interdisciplinary, cross-department and cross-industry.