[目的/意义]多元主体交互已成为在线慢病社区的突出特征和发展模式，探索在线慢病社区多元主体交互的关系网络结构特征和行为模式能为制定促进多元主体交互和在线慢病社区可持续发展的针对性策略提供参考。[方法/过程]在分析在线慢病社区多元主体交互概念特征、交互行为模型和交互关系模型基础上，基于“淋巴瘤之家”的用户交互数据构建在线慢病社区多元主体交互关系网络，继而引入多维网络结构特征指标分析多元主体交互的网络结构韧性、动态演化特征和行为模式。[结果/结论]在线慢病社区多元主体以跨主体交互模式、关键主体引导交互模式、多核心主体交互模式和中介者协调交互模式广泛参与社区交互活动，建立了沟通互动性相对较弱、韧性水平较低、网络结构动态演化的稀疏关系网络。

[Purpose/significance] Multi-subject interaction has emerged as a prominent characteristic and develop⁃ment model in online chronic disease communities. Exploring the relational network structure characteristics and be⁃havioral patterns of multi-subject interaction in these communities can provide valuable insights for formulating target⁃ed strategies to promote multi-subject interaction and sustainable development of online chronic disease communities.[Method/process] Based on the analysis of the conceptual characteristics, interaction behavior models and interaction relationship models of multi-subject interaction in online chronic disease communities, a multi-subject interaction re⁃lationship network was constructed using sample data from the“Lymphoma House”. Subsequently, multi-dimensional network structure characteristic indicators were introduced to analyze the resilience, dynamic evolution features, and behavioral patterns of the multi-subject interaction. [Result/conclusion] The multi-subject of online chronic disease community participates in community interaction activities with cross-agent interaction mode, key subject-led interac⁃tion mode, multi-core subject interaction mode and mediator-coordinated interaction mode. Under these interaction models, a sparse relational network with relatively weak communication interactivity, low resilience, and dynamically evolving network structures has been established.