[目的/意义]对信息流行病管理实践经验进行系统性整合与学理性分析，为丰富理论体系和优化实践效能提供参考。[方法/过程]采用网络调研法，收集联合国教科文组织、世界卫生组织、欧盟委员会等机构实施的信息流行病管理实践举措；采取质性研究方法，遵循“素材选取—素材离散化—条目聚类”的步骤进行系统性整合，提取信息流行病的管理对策；对管理对策进行学理性分析，阐明管理对策的应用原则；以应用原则为指导，采用“阶段—对策”二维表作为分析框架，剖析管理对策的应用方式。[结果/结论]提出了面向信息流行病的“管理对策—应用原则—应用方式”的体系化应对框架。信息流行病的管理对策包括四个维度：面向信息源要素的管理对策、面向信息内容要素的管理对策、面向信息接收者要素的管理对策、环境优化对策；应用管理对策时应当遵循因时制宜、拉平曲线、快速响应、主动预防、长期努力、协同合作等原则；应当将管理对策与信息流行病演化阶段相结合，针对不同阶段的特性优先应用不同的对策组合。
[Purpose/significance] This study aims to systematically integrate and theoretically analyze practical expe⁃riences in infodemic management. It seeks to enrich the theoretical landscape and optimize the efficacy of practical in⁃terventions. [Method / process] A web-based survey method was employed to collect infodemic management initia⁃tives implemented by major international bodies, including UNESCO, the World Health Organization and the Europe⁃an Commission. Utilizing qualitative research methodologies, these beneficial practices were systematically integrated following a rigorous procedure of "material selection, discretization, and item clustering" to extract management strate⁃gies for infodemics. These strategies underwent theoretical analysis to elucidate their application principles. Guided by these principles, a two-dimensional "stage-countermeasure" matrix was adopted as an analytical framework to dissect the application methods of these strategies. [Result/conclusion] The study proposes a systematic response framework for infodemics comprising "management strategies-application principles-application methods". The management strategies are categorized into four dimensions: strategies targeting information source elements, information content ele⁃ments, information receiver elements, and environmental optimization. The application of these strategies should adhere to principles such as contextual adaptability, curve flattening, rapid response, proactive prevention, sustained effort, and collaborative synergy. Furthermore, it is imperative to align strategies with the evolutionary stages of the infodemic, prior⁃itizing distinct combinations of strategies based on the specific characteristics of each stage.
